No spacers - your clearance will be plenty tight enough as it is.
All of 1, 2 and 3 will work. 4 is a non-starter, as a 245 is far too wide for a 7 inch rim. The 205/55 is the best fit for 4 reasons. First, it is the "best size for a 7 inch rim as it is nicely stretched and performs considerably better than on a 6. Second it is the closest of the options in rolling circumference to the 245/45 you have for the rear. Third, it should not rub on the fender lip - which is where you may have clearance issues (because the 7 compared to a 6 has all the extra width on the outside). Fourth, it keeps the ride compliance that most people value on the road because of the slightly taller sidewall. The 205/50 offers slightly better performance as its shorter sidewall will give a little sharper turn-in and less flex and because it is smaller (ie less tall) it often doesn't rub where a 205/55 may rub, but, because it is smaller, it looks a little goofy and results in a lower front ride height. The 225/50 is on paper a better match to a 245/45 in terms of understeer/oversteer balance. Many people think that a 205/245 combo will give too much understeer. They are right, to some extent, but in my experience it really doesn't change things enough to worry about. The 2 problems with a 225/50 on a 7 up front are that the tyre works better on an 8 than 7, so it doesn't in reality offer much more than a 205, and secondly, it makes rubbing on the fender a strong possibility - in fact almost a certainty.
From my experience, I would choose on the basis of your alignment specs - please let us know what they are. If you have between something like 0.5 degrees negative camber you will not fit anything bigger than a 205 without rubbing the fender lip. Even then, you may need to roll the lip. If you have 1 degree negative you should be ok with 205s. If you have 1.25 degrees you might just squeeze a 225 in there if you roll the fender lips as well. It is not normally possible to get more than 1.25 degrees neg without a strut brace to crank the strut towers together a bit or other modifications for more camber, but, if you can get 1.5 degrees neg you should get a 225 in ok.
Your 4th option should have been a 225/45, which is the same size as a 205/50 in height and has the extra width. This sometimes fits where a 225/50 will rub.
One other thing to note, stiff torsion bars make things a lot easier - but I assume you don't have those.
Finally, all our cars are a little different. The LHS generally seems to be the tighter fender, so try that first. If you have to roll the fender lip, it is no big deal. Just use a heat gun to soften the paint before you start and take it slowly. A baseball bat works well as a tool for fender rolling and you normally only need to do the 12 inches along the top. If you have max castor in your alignment then you may rub a little forward of the highest point of the arch.
HTH,
Richard